Primary Identifier | MGI:5560198 | Allele Type | Transgenic |
Attribute String | Inducible, Inserted expressed sequence, Transactivator | Gene | Tg(tetO-Mirlet7a/Mir155,Vil1-rtTA)#Aru |
Strain of Origin | (C57BL/6 x SJL)F1 | Induced With | doxycycline/tetracycline |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The construct consists of the TRE3G (a third-generation tet-responsive promoter), and EmGFP region, a fusion of Mirlet7a to a modified mir155 terminal loop, an SV40 polyadenylation signal, a 13 kb mouse Vil1 promoter, and a rtTA-M2 sequence. The Mirlet7a/mir155 fusion shRNA is not recognized by LIN28A or LIN28B. |