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Allele : Cdk5r1<tm2.1Lht> cyclin dependent kinase 5, regulatory subunit 1; targeted mutation 2.1, Li-Huei Tsai

Primary Identifier  MGI:5560495 Allele Type  Targeted
Gene  Cdk5r1 Transmission  Germline
Strain of Origin  129 Is Recombinase  false
Is Wild Type  false
molecularNote  The deltap35-3xHA knock-in cassette encodes for deletion of the six amino acid residues adjacent to the calpain-cleavage site (delta93-98) and replaces the alanine residue in the cleavage site for leucine., The cassette was generated via two sequential recombination reactions. The final targeting vector contains this deltap35-3xHA knock-in cassette and a loxP site-flanked NEO cassette. Mutant mice were bred with Meox2-cre mice to remove the neo selection cassette.
  • mutations:
  • Intragenic deletion,
  • Nucleotide substitutions
  • synonyms:
  • deltap35KI,
  • deltap35KI,
  • delta p35-3xHA,
  • delta p35-3xHA
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

7 Publication categories