Primary Identifier | MGI:5563691 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(SV40-KLK7)1010Teg |
Strain of Origin | (C57BL/6J x CBA)F2 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The human KLK7 cDNA is under the control of the SV40 early enhancer and promoter elements. Three lines were established; 103, 107, and 1010, however only this line shows a skin phenotype. Enzyme-linked immunosorbent assay confirmed protein expression in skin, intestines, and lung and immunoblotting indicates that proteolytically active enzyme is produced. |