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Allele : Crb3<tm1.2Bmar> crumbs family member 3; targeted mutation 1.2, Ben Margolis

Primary Identifier  MGI:5563835 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Crb3
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  An FRT-flanked neomycin resistance cassette was inserted downstream of exon 2. Exon 3 was replaced with a floxed exon 3-GFP fusion. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed the modified exon 3. Western blot analysis confirmed the absence of protein expression in E18.5 lungs and kidneys.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele