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Allele : Dhfr<orana> dihydrofolate reductase; orana

Primary Identifier  MGI:5563476 Allele Type  Chemically induced (ENU)
Attribute String  Null/knockout Gene  Dhfr
Inheritance Mode  Recessive Strain of Origin  C57BL/6JAnu
Is Recombinase  false Is Wild Type  false
Project Collection  APF ENU Mutagenesis
molecularNote  A single base substitution (A to G) of base pair 885 in exon 5 (ENSMUSE00000120178) was detected. This mutation results in an ACA (Thr)-to-GCA (Ala) change of amino acid 136. DHFR protein was essentially undetectable in homozygous embryos.
  • mutations:
  • Single point mutation
  • synonyms:
  • Dhfr<Thr136Ala>,
  • Dhfr<Thr136Ala>,
  • Dhfr<ora>,
  • ENU15:B10:025,
  • Dhfr<ora>,
  • ENU15:B10:025
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories