Primary Identifier | MGI:5563476 | Allele Type | Chemically induced (ENU) |
Attribute String | Null/knockout | Gene | Dhfr |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6JAnu |
Is Recombinase | false | Is Wild Type | false |
Project Collection | APF ENU Mutagenesis |
molecularNote | A single base substitution (A to G) of base pair 885 in exon 5 (ENSMUSE00000120178) was detected. This mutation results in an ACA (Thr)-to-GCA (Ala) change of amino acid 136. DHFR protein was essentially undetectable in homozygous embryos. |