Primary Identifier | MGI:5565229 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Macroh2a2 |
Transmission | Germline | Strain of Origin | (C57BL/6 x 129S4/SvJae)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting vector was designed to insert a loxP-flanked PGKneo cassette upstream of exon 2 and loxP site downstream of exon 2. Mutant mice were bred with mice carrying Tg(EIIa-cre)C5379Lmgd to remove exon 2 and the neo cassette. Polymorphisms near the gene demonstrated that the targeted gene is in a genomic region derived from the 129S4/Jae parent of the embryo from which the ES cell line was generated. |