Primary Identifier | MGI:5567088 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(ACTB-Tbx1,-GFP)1Bald |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The single-copy transgene comprises a chicken beta actin promoter followed by a loxP-flanked neomycin resistance cassette (neor) with a triple polyadenylation signal, a full-length cDNA encoding mouse T-box 1 protein (TBX1) with a Myc epitope tag, an internal ribosomal entry site (IRES) and a green fluorescent protein coding sequence. Upon cre recombinase-mediated recombination, neor is excised and the Tbx1 cDNA is expressed under control of the beta-actin promoter. |