| Primary Identifier | MGI:5568409 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Abcc8 |
| Transmission | Germline | Strain of Origin | 129S2/SvPas |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A G to A missense mutation was introduced to correspond to the GAG to AAG mutation found in human SUR1-E1506K carriers. Cre-mediated recombination removed the floxed neomycin resistance cassette inserted downstream of exon 36. Western blot analysis confirmed reduced protein expression in the islet. |
