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Allele : Gt(ROSA)26Sor<tm1(ETV6/SYK)Hjum> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Hassan Jumaa

Primary Identifier  MGI:5568502 Allele Type  Targeted
Attribute String  Conditional ready, Constitutively active, Humanized sequence, Inserted expressed sequence, Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting vector introduced into the locus a splice acceptor, loxP site, RFP, FRT-flanked neomycin resistance cassette, polyadenylation STOP sequence, loxP site and fusion of human ETV6 and SYK. The fusion product in a constitutively active form of Syk identified in human patients with myelodysplastic syndrome.
  • mutations:
  • Insertion
  • synonyms:
  • TS,
  • TS,
  • TEL-SYK,
  • TEL-SYK
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1 Feature

Genome

2 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories