Primary Identifier | MGI:5568502 | Allele Type | Targeted |
Attribute String | Conditional ready, Constitutively active, Humanized sequence, Inserted expressed sequence, Reporter | Gene | Gt(ROSA)26Sor |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting vector introduced into the locus a splice acceptor, loxP site, RFP, FRT-flanked neomycin resistance cassette, polyadenylation STOP sequence, loxP site and fusion of human ETV6 and SYK. The fusion product in a constitutively active form of Syk identified in human patients with myelodysplastic syndrome. |