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Allele : Lats1<tm1.1Jfm> large tumor suppressor; targeted mutation 1.1, James F Martin

Primary Identifier	MGI:5568586	Allele Type	Targeted
Attribute String	Conditional ready	Gene	Lats1
Transmission	Germline	Strain of Origin	(C57BL/6Brd-Tyr<c-Brd> x 129S6/SvEvTac)F1
Is Recombinase	false	Is Wild Type	false

molecularNote

A targeting vector was designed to flank exon 4 with loxP sites. This construct also contained a frt-flanked neomycin resistance (neo) cassette. FLP-mediated recombination removed the frt-flanked neo cassette.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Lats1<f>,
Lats1<f>

earliestPublication:
Heallen T, et al. (2013) Hippo signaling impedes adult heart regeneration. Development 140(23):4683-90

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

58 Publication categories

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