|  Help  |  About  |  Contact Us

Allele : Hprt1<tm365a(Ple266-icre/ERT2)Ems> hypoxanthine phosphoribosyltransferase 1; targeted mutation 365a, Elizabeth M Simpson

Primary Identifier  MGI:5568246 Allele Type  Targeted
Attribute String  Conditional ready, Inducible, Recombinase Gene  Hprt1
Transmission  Germline Strain of Origin  B6N.Cg-A<w-J> Hprt1<b-m3>
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false Project Collection  EUCOMMTOOLS
molecularNote  The transgene was designed with an HS4 insulator region, the 2982 bp Ple266 minipromoter (derived from a portion of the endogenous promoter and one upstream putative regulatory element from the human S100 calcium binding protein B - S100B ), a chimeric intron cassette, the iCre/ERT2 fusion gene (with F3-frt sites flanking the ERT2 sequences), the mut6-WPRE element, an SV40 early polyA signal, an additional HS4 insulator region, a human HPRT complementary sequence (containing exon 1, intron 1, exon 2, and part of intron 2), a mouse 3' Hprt homology arm, an I-Sce linearization cut site, and a mouse 5' Hprt homology arm.
  • mutations:
  • Insertion
  • synonyms:
  • Ple266-icre/frt/ERT2/frt,
  • mEMS5950,
  • mEMS5950,
  • Ple266-icre/frt/ERT2/frt,
  • S100B-creERT2,
  • S100B-creERT2
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

1 Driven By

4 Publication categories