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Allele : Serpina12<tm1Jwada> serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12; targeted mutation 1, Jun Wada

Primary Identifier	MGI:5568548	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Serpina12
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false

molecularNote

A floxed neomycin resistance cassette replaced exon 2. Western blot analysis confirmed the absence of expression in the serum of mice fed a high fat, high sucrose diet.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

earliestPublication:
Nakatsuka A, et al. (2012) Vaspin is an adipokine ameliorating ER stress in obesity as a ligand for cell-surface GRP78/MTJ-1 complex. Diabetes 61(11):2823-32

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

6 Publication categories

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