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Allele : Dmd<tm1.1Know> dystrophin, muscular dystrophy; targeted mutation 1.1, Kirk Knowlton
Primary Identifier  MGI:5569634 Allele Type  Targeted
Gene  Dmd Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  Two point mutations in exon 50 result in the amino acid substitution of proline for lysine at position 2425 (L2425P) and aspartic acid for serine at position 2426 (S2426D). This mutations prevent cleavage by protease 2A. Cre-mediated recombination removed the floxed neomycin resistance cassette.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Dys<KI>,
  • Dys<KI>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories





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