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Allele : Tg(TG-SV40)#Cled transgene insertion, Catherine Ledent

Primary Identifier  MGI:5569755 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(TG-SV40)#Cled
Strain of Origin  (C57BL/6J x DBA/2J)F2 Is Recombinase  false
Is Wild Type  false
description  Phenotypic Similarity to Human Syndrome: Anaplastic Thyroid Cancer J:209788
molecularNote  This transgene contained the bovine thyroglobulin (TG) promoter and expressed the viral SV40 large T antigen and small t antigen. Thirty founder mice were generated. Two transgenic lines were established but neither was specifically named. Immunofluorescence indicates antigen expression in the nuclei of all thyroid cells, but absent in connective or vascular tissue in the thyroid or in other tissues.
  • mutations:
  • Insertion
  • synonyms:
  • Tg-TAg,
  • bTg-LTSV40,
  • TgAgT,
  • TgAgT,
  • bTg-LTSV40,
  • Tg-TAg
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories