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Allele : Lmna<tm1.2Yxz> lamin A; targeted mutation 1.2, Yixian Zheng
Primary Identifier  MGI:5575530 Allele Type  Targeted
Attribute String  Null/knockout Gene  Lmna
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 2. An FRT-flanked puromycin resistance cassette with a 3' loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 2. Immunofluorescence confirmed the absence of lamin A and C in mouse embryonic fibroblasts.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Lmna<delta>,
  • Lmna<delta>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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