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Allele : Atg5<tm1.1Myok> autophagy related 5; targeted mutation 1.1, Minesuke Yokoyama

Primary Identifier	MGI:5572834	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Atg5
Transmission	Germline	Strain of Origin	129S/SvEv-Gpi1<c>
Is Recombinase	false	Is Wild Type	false

molecularNote

A targeting vector was designed to flank exon 3 with loxP sites. Cre-mediated recombination removes both exon 3 and the selection cassette.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

earliestPublication:
Wang S, et al. (2013) Transient activation of autophagy via Sox2-mediated suppression of mTOR is an important early step in reprogramming to pluripotency. Cell Stem Cell 13(5):617-25

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

5 Publication categories

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