Primary Identifier | MGI:5572835 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Sox2 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted usptream of the coding exon and an frt flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of the exon. The frt flanked neo cassette used for selection was removed by germ line, flp mediated recombination. Cre-mediated recombination removed the coding exon. |