| Primary Identifier | MGI:5574450 | Allele Type | Targeted |
| Attribute String | Conditional ready, Dominant negative | Gene | Dpp9 |
| Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP-flanked exon 20 with amino acid substitution of serine to alanine at position 729 (S729A), followed by a FRT-PGK-neo-FRT cassette was inserted by homologous recombination. Flp-mediated recombination removed the neo-cassette. This point mutation results in an enzyme inactive form of the protein. No change in subcellular localization was detected by immunohistochemical analysis. |
