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Allele : n-TRtct5<m1J> nuclear encoded tRNA arginine 5 (anticodon TCT); mutation 1, Jackson

Primary Identifier  MGI:5575489 Allele Type  Spontaneous
Attribute String  Not Specified Gene  n-TRtct5
Inheritance Mode  Recessive Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  This C-to-T transition, the T variant of SNP rs46447118, found in C57BL/6J and C57BL/6JEiJ but not any of the other 18 inbred strains tested, is in nucleotide 50 in the stem of the T loop and impairs maturation, leading to accumulation of a 105 nucleotide pre-tRNA band with leader and trailer sequences instead of the usual 115 nucleotide pre-tRNA, and also diminishes aminoacylation of this isodecoder.
  • mutations:
  • Single point mutation
  • synonyms:
  • n-TRtct5<rs4644711-T>,
  • rs46447118,
  • n-TRtct5<rs4644711-T>,
  • n-Tr20<C57BL/6J>,
  • rs46447118,
  • n-Tr20<C57BL/6J>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

7 Carried By

0 Driven By

22 Publication categories