| Primary Identifier | MGI:5576381 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Cd68-BCL2)535Medz |
| Strain of Origin | 129 x C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| description | The original background of this transgene was "C57BL/6.129/Sv" (J:82809). |
| molecularNote | This transgene contains the promoter of the CD68 antigen gene driving expression of human B cell leukemia/lymphoma 2 (BCL2). Immunoblot analysis demonstrates expression of human BCL2 in dendritic cells (DCs) and bone-marrow derived macrophages (BMMs) of mice of this transgenic line, but not in BMMs or DCs of non-transgenic littermates. |
