|  Help  |  About  |  Contact Us

Allele : Slc1a2<tm1.1Ncd> solute carrier family 1 (glial high affinity glutamate transporter), member 2; targeted mutation 1.1, NC Danbolt

Primary Identifier  MGI:5576462 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Slc1a2
Transmission  Germline Strain of Origin  (129S6/SvEvTac x C57BL/6J)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted into intron 2 and an frt-neo-frt-loxP cassette was inserted into intron 4, floxing exons 3 and 4 of the Slc1a2 gene from the bacterial artificial chromosome clone RP24-315H4. The neomycin cassette was removed via FLP-mediated recombination, leaving exons 3 and 4 floxed by loxP sites. Cre-mediated recombination can be used to remove exons 3 and 4 which results in a frameshift deletion.
  • mutations:
  • Insertion
  • synonyms:
  • EAAT2-flox,
  • EAAT2-flox
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

8 Publication categories