| Primary Identifier | MGI:5577178 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Thy1-FUS*)19Vlb |
| Strain of Origin | C57BL/6 x CBA | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | This transgene consists of a fragment of human FUS 1-359 cDNA including 9 bp of 5'-UTR under the control of the Thy1 promoter. This FUS variant is predominantly cytoplasmic as it lacks the nuclear localization signal, highly aggregate-prone, and lacks a region responsible for RNA recognition and binding. Western blot confirmed expression in neural tissues. |
