Primary Identifier | MGI:5578034 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Tbc1d10c |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted upstream of exon 4. A floxed neomycin resistance cassette was inserted downstream of exon 5. Cre-mediated recombination removed the selection cassette and exons 4 and 5. Western blot analysis confirmed the absence of protein expression in the spleen and thymus. |