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Allele : Tg(Prnp-MAPT*)2652Gds transgene insertion 2652, Gerard Schellenberg
Primary Identifier  MGI:5578354 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Prnp-MAPT*)2652Gds
Strain of Origin  (C57BL/6J x C3H/HeJ)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  The 1N4R brain isoform of human MAPT (microtubule associated protein, tau) is expressed under the control of the mouse neuron-specific prion protein (PrP) promoter. Hemizygous mice exhibit approximate 12-fold overexpression of human tau relative to endogenous mouse tau and show consistent transmission of approximately 143+/-20 copies of the transgene.
  • mutations:
  • Insertion
  • synonyms:
  • Tg(Thy1-MAPT*)2652Gds,
  • Tg(Thy1-MAPT*)2652Gds,
  • Tau4RTg2652,
  • Tg2652,
  • Tg(pThy1.2-MAPT*)2652Gsd,
  • Tau4RTg2652,
  • Tg2652,
  • Tg(pThy1.2-MAPT*)2652Gsd
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

5 Publication categories





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