Primary Identifier | MGI:5581668 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Mafb |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The single coding exon was flanked with loxP sites. An FRT-flanked neomycin resistance cassette was inserted downstream of the coding exon. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed the coding exon. Western blot analysis confirmed the absence of protein expression in E16.5 embryos. |