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Allele : Col1a1<tm3(CAG-IDH2*R140Q)Kkw> collagen, type I, alpha 1; targeted mutation 3, Kwok-Kin Wong
Primary Identifier  MGI:5582192 Allele Type  Targeted
Attribute String  Conditional ready, Humanized sequence, Inserted expressed sequence Gene  Col1a1
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Is Recombinase  false Is Wild Type  false
molecularNote  The construct was designed to insert (from 5' to 3') an FRT site, the chicken beta-actin promoter (CAG), a loxP flanked stop cassette, the human IDH2 with the R140Q mutation, a PGK hygro-polyA sequence, and a second FRT site into the mouse collagen A1 locus.
  • mutations:
  • Insertion
  • synonyms:
  • IDH2<R140Q>,
  • IDH2<R140Q>,
  • Col1a1<tm1(CAG-IDH2*R140Q)Kkw>,
  • Col1a1<tm1(CAG-IDH2*R140Q)Kkw>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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