| Primary Identifier | MGI:5582769 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Poli |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted upstream of exon 5. An FRT-flanked neomycin resistance cassette with a 3 loxP site was inserted downstream of exon 7. Cre-mediated recombination removed the selection cassette, exon 6 and exon 7. These exons encode the conserved motif IV and V (helix-hairpin-helix region for DNA binding). Western blot analysis confirmed the absence of full-length and truncated version of the protein in testes. |
