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Allele : Tyr<em2Utr> tyrosinase; endonuclease-mediated mutation 2, University of Tsukuba Laboratory Animal Resource Center
Primary Identifier  MGI:5582798 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Tyr
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  Arginine codon 77 (CGT) in exon 1 was changed to leucine (CTT) (c.230G>T:p.R77L) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. This allele was derived from mouse founder line #1 which also carries the 5-nucleotide-deletion allele Tyrem1Utr in trans.
  • mutations:
  • Single point mutation
  • synonyms:
  • Tyr<G291T>,
  • Tyr<G291T>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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