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Allele : Ryr2<tm2Hhv> ryanodine receptor 2, cardiac; targeted mutation 2, Hector H Valdivia
Primary Identifier  MGI:5583980 Allele Type  Targeted
Attribute String  Humanized sequence, Null/knockout Gene  Ryr2
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
molecularNote  A modified exon 48 containing a valine to phenylalanine (V2475F) mutation and a translationally silent Mlu-I restriction site replaced the endogenous exon. A loxP-flanked neomycin cassette was also inserted downstream of the modified exon and was subsequently removed by mating founder mice with EIIa-cre transgenic mice.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • RyR2-V2475F,
  • RyR2-V2475F
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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