| Primary Identifier | MGI:5587034 | Allele Type | Targeted |
| Attribute String | Conditional ready | Gene | Ttc21b |
| Transmission | Germline | Strain of Origin | C57BL/6N |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | KOMP-CSD |
| molecularNote | The L1L2_gt1 cassette was inserted at position 66079515 of Chromosome 2 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 66080377. The critical exon, exon 4, is thus flanked by loxP sites. A "conditional ready" (floxed) allele is created by flp recombinase expression in mice carrying this allele, removing the lacZ/neomycin cassette, but leaving exon 4 flanked by loxP sites. |
