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Allele : Gt(ROSA)26Sor<tm2(Sirt1)Ktm> gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Tadahiro Kitamura

Primary Identifier  MGI:5586719 Allele Type  Targeted
Attribute String  Conditional ready, Inserted expressed sequence Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting construct introduced into the locus a splice acceptor, floxed neomycin resistance/STOP cassette and cDNA with nucleotide substitution(s) result(s) in the amino acid substitution of tyrosine for histidine at position 355 (H355Y). This mutation is predicted to generate an enzyme dead protein.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Rosa26<Sirt1-H355Y>,
  • Rosa26<Sirt1-H355Y>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories