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Allele : Gt(ROSA)26Sor<tm2(ITK/Syk)Hjum> gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Hassan Jumaa
Primary Identifier  MGI:5586728 Allele Type  Targeted
Attribute String  Conditional ready, Humanized sequence, Inserted expressed sequence Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct introduced into the locus a splice acceptor, loxP site, FRT site, neomycin resistance cassette, FRT site, STOP sequence, loxP site and fusion of the human cDNAs for ITK and SYK. This fusion is found in peripheral T cell lymphomas (PTCLs) patients harboring the t(5;9)(q33;q22) translocation.
  • mutations:
  • Insertion
  • synonyms:
  • ROSA26-ITK-Syk,
  • ROSA26-ITK-Syk
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1 Feature

Genome

2 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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