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Allele : Skint1<m1Tac> selection and upkeep of intraepithelial T cells 1; mutation 1, Taconic

Primary Identifier	MGI:5588374	Allele Type	Spontaneous
Gene	Skint1	Inheritance Mode	Recessive
Strain of Origin	FVB/NTac	Is Recombinase	false
Is Wild Type	false

molecularNote

A spontaneous point mutation (GAA to TAA) results in the amino acid substitution of a stop codon for glutamate at position 324 (Q324X). This mutation is fixed in the FVB/NTac strain.

mutations:
Nucleotide substitutions

synonyms:
Skint1 <Glu324Stop>,
Skint1<FVB(Tac)>,
Skint1<FVB(Tac)>,
Skint1 <Glu324Stop>

earliestPublication:
Boyden LM, et al. (2008) Skint1, the prototype of a newly identified immunoglobulin superfamily gene cluster, positively selects epidermal gammadelta T cells. Nat Genet 40(5):656-62

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

12 Publication categories

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