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Allele : Prmt1<tm1c(EUCOMM)Wtsi> protein arginine N-methyltransferase 1; targeted mutation 1c, Welcome Trust Sanger Institute

Primary Identifier	MGI:5587827	Allele Type	Targeted
Attribute String	Conditional ready	Gene	Prmt1
Transmission	Germline	Strain of Origin	C57BL/6N
Is Recombinase	false	Is Wild Type	false
Project Collection	EUCOMM

molecularNote

Prmt1^{tm1a(EUCOMM)Wtsi} (MGI:4432476) were bred to mice expressing flp recombinase to remove selection elements leaving the critical exons floxed.

mutations:
Insertion

earliestPublication:
Hashimoto M, et al. (2016) Severe Hypomyelination and Developmental Defects Are Caused in Mice Lacking Protein Arginine Methyltransferase 1 (PRMT1) in the Central Nervous System. J Biol Chem 291(5):2237-45

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

22 Publication categories

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