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Allele : Tg(CD2-Mir181d)38Oers transgene insertion 38, Nicolai S C van Oers

Primary Identifier	MGI:5588400	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	Tg(CD2-Mir181d)38Oers
Strain of Origin	C57BL/6	Is Recombinase	false
Is Wild Type	false

molecularNote

The human promoter (VA-hCD2) drives thymocyte and peripheral T cell-specific expression of a 394 bp fragment with an intact Mir181d but lacking the first 28 nulceotides of Mir181c. Lines 8 and 28 were generated with 2- and 6-fold expression, respectively.

mutations:
Insertion

synonyms:
Tg-38,
Tg-38

earliestPublication:
Belkaya S, et al. (2014) Transgenic expression of microRNA-181d augments the stress-sensitivity of CD4(+)CD8(+) thymocytes. PLoS One 9(1):e85274

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

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