| Primary Identifier | MGI:5588460 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(MECP2*R111G/EGFP)1Hzo |
| Strain of Origin | FVB/N | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A human PAC (PAC671D9) containing only the MECP2 locus and regulatory elements was modified to introduce a R111G (AGG to GGG) missense mutation in the methyl-CpG binding domain (MPD) of exon 3 and a C-terminal GFP tag. Expression of the transgene parallels that of endogenous MECP2 in the brain. |
