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Allele : Pten<tm3.1Ppp> phosphatase and tensin homolog; targeted mutation 3.1, Pier Paolo Pandolfi

Primary Identifier  MGI:5606180 Allele Type  Targeted
Gene  Pten Transmission  Germline
Strain of Origin  (C57BL/6 x 129S4/SvJae)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  Nucleotide substitutions in exon 5 were introduced by homologous recombination to alter codon 124 from one encoding cysteine to encoding serine (Cys124Ser). An adjacent loxP-flanked neomycin selection cassette that was inserted into intron 5 was removed by cre-mediated recombination.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • PTENC124S,
  • Pten<C124S>,
  • Pten<C124S>,
  • PTENC124S
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories