Primary Identifier | MGI:5607164 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Cd22 |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | The crullers mutation is in Cd22: a T to C transition at base pair 30,869,883 (v38) on chromosome 7, or base pair 10,460 in the GenBank genomic region NC_000073. This corresponds to nucleotide 2,045 in the mRNA sequence NM_009845 within exon 8 of 14 total exons or nucleotide 2,170 in the mRNA sequence NM_001043317 in exon 10 of 16 total exons. The mutation results in a serine (S) to proline (P) substitution at position 603 (S603P) in both CD22 isoforms. |