|  Help  |  About  |  Contact Us

Allele : Cd22<m2Btlr> CD22 antigen; mutation 2, Bruce Beutler

Primary Identifier  MGI:5607164 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Cd22
Inheritance Mode  Recessive Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
molecularNote  The crullers mutation is in Cd22: a T to C transition at base pair 30,869,883 (v38) on chromosome 7, or base pair 10,460 in the GenBank genomic region NC_000073. This corresponds to nucleotide 2,045 in the mRNA sequence NM_009845 within exon 8 of 14 total exons or nucleotide 2,170 in the mRNA sequence NM_001043317 in exon 10 of 16 total exons. The mutation results in a serine (S) to proline (P) substitution at position 603 (S603P) in both CD22 isoforms.
  • mutations:
  • Single point mutation
  • synonyms:
  • crullers,
  • crullers
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele