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Allele : Ptbp2<tm1.2Dblk> polypyrimidine tract binding protein 2; targeted mutation 2.1, Douglas Black

Primary Identifier  MGI:5608588 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ptbp2
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  An FRT-flanked PGK-neomycin cassette and loxP site were introduced to intron 3 and a loxP site was placed in intron 4 via homologous recombination. The neomycin cassette was excised from resultant mice through crosses with a Flp recombinase-expressing strain, leaving exon 4 flanked by loxP sites. Cre-mediated recombination removed exon 4. Immunoblot confirms the absence of protein.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories