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Allele : Lepr<m6Btlr> leptin receptor; mutation 6, Bruce Beutler

Primary Identifier  MGI:5609704 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Lepr
Inheritance Mode  Not Specified Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
molecularNote  The molecular lesion is a T to A transversion at base pair 101,745,645 (v38) on chromosome 4, or base pair 28,239 in GenBank genomic region NC_000070; this corresponds to nucleotide 1,181 in the mRNA sequence NM_146146, within exon 5 of 19 total exons. The mutation results in a methionine (M) to lysine (K) substitution at amino acid position 210 (M210K) of the protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • paleo,
  • paleo
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories