Primary Identifier | MGI:5607749 | Allele Type | Targeted |
Attribute String | Conditional ready, Reporter | Gene | Fas |
Transmission | Germline | Strain of Origin | B6(Cg)-Tyr<c-2J>/J |
Is Recombinase | false | Is Wild Type | false |
description | ES cell line = CSL2J2 |
molecularNote | Using a BAC-based targeting approach, a loxP-splice acceptor (SA) site was introduced to intron 1 of the Fas gene and an FRT-PGK-Neo-FRT-loxP-SA-human placental alkaline phosphatase (PLAP)-pA was placed in intron 9. Flp-mediated recombination removed the neomycin cassette. |