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Allele : Fas<tm1.1(ALPP)Chnd> Fas cell surface death receptor; targeted mutation 1.1, Christopher Henderson

Primary Identifier  MGI:5607749 Allele Type  Targeted
Attribute String  Conditional ready, Reporter Gene  Fas
Transmission  Germline Strain of Origin  B6(Cg)-Tyr<c-2J>/J
Is Recombinase  false Is Wild Type  false
description  ES cell line = CSL2J2
molecularNote  Using a BAC-based targeting approach, a loxP-splice acceptor (SA) site was introduced to intron 1 of the Fas gene and an FRT-PGK-Neo-FRT-loxP-SA-human placental alkaline phosphatase (PLAP)-pA was placed in intron 9. Flp-mediated recombination removed the neomycin cassette.
  • mutations:
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories