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Allele : Hprt1<tm1(CAG-Glra3*)Jcme> hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Jochen C Meier

Primary Identifier  MGI:5608589 Allele Type  Targeted
Attribute String  Conditional ready, Inserted expressed sequence Gene  Hprt1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A region encompassing the 5' UTR through intron 2 was replaced with a construct containing CAG-loxP-stop-loxP-Glra3 cDNA (rat, long variant with a P185L substitution and containing exon 8a) and human HPRT promoter and exons 1 and 2. The CAG-Glra3 and Hprt sequences are expressed in opposite directions. The Glra3 sequence also has an HA tag.
  • mutations:
  • Insertion
  • synonyms:
  • Hprt<tm1(CAG-Glra3*)GW>,
  • Hprt<alpha3L185L>,
  • Hprt<tm1(CAG-Glra3*)GW>,
  • Hprt<alpha3L185L>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories