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Allele : Igh<tm1(IGH)Vlcg> immunoglobulin heavy chain complex; targeted mutation 1, Velocigene

Primary Identifier  MGI:5609985 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence, Null/knockout Gene  Igh
Transmission  Germline Strain of Origin  (129S6/SvEvTac x C57BL/6NTac)F1
Is Recombinase  false Is Wild Type  false
molecularNote  Using BAC recombineering roughly 3 Mbp of the mouse locus including all of the Vh Dh and Jh gene segments was replaced with 340 kb of contiguous human sequence containing the equivalent human gene segments. The proximal junction of the replacement was placed about 200 bp downstream from the last J segment and the distal junction was placed about 9 kbp downstream from J558.55.
  • mutations:
  • Insertion,
  • Intergenic deletion
  • synonyms:
  • 18hVH,
  • 18hVH
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

2 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele