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Allele : Rr29<tm2Bobh> regulatory region 29; targeted mutation 2, Robert E Hill

Primary Identifier  MGI:5613149 Allele Type  Targeted
Attribute String  Modified regulatory region Gene  Rr29
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site flanked lacZ and neomycin resistance gene cassette was inserted downstream of the Shh enhancer in intron 5 of the Lmbr1 gene and the 3' end of the region including all but the first ETS binding site was deleted via homologous recombination. The one remaining ETS1/GABPA binding site was mutated to prevent binding of ETS1/GABPA .
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • ZRS<ETS+LACZ>,
  • ZRS<ETS+LACZ>
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1 Feature

Genome

0 Expresses

1 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories