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Allele : Tg(CMV-Plaur*)19Lbh transgene insertion 19, Lawrence B Holzman

Primary Identifier  MGI:5613978 Allele Type  Transgenic
Attribute String  Conditional ready, Inserted expressed sequence, No functional change Gene  Tg(CMV-Plaur*)19Lbh
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  The construct is designed with the CMV-IE enhancer/chicken beta-actin hybrid promoter (CAG; from the pCAGGS vector), a loxP-flanked transcriptional STOP cassette (containing beta galactosidase and a polyadenylation signal), and the soluble form of the murine urokinase-type plasminogen activator receptor (Plaur) gene. The soluble form of Plaur (suPAR) encodes a 60 kDa truncated protein, lacking the glycophosphatidylinositol (GPI) anchored three domain (commonly referred to as D1, D2, D3) protein.
  • mutations:
  • Insertion
  • synonyms:
  • CMVflox-suPAR-FL,
  • CMVflox-suPAR-FL
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories