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Allele : Trpc4<tm1.1Clph> transient receptor potential cation channel, subfamily C, member 4; targeted mutation 1.1, David E Clapham

Primary Identifier  MGI:5615468 Allele Type  Targeted
Attribute String  Null/knockout Gene  Trpc4
Transmission  Germline Strain of Origin  129S1/SvImJ
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 4 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 4 via homologous recombination. Cre mediated recombination removed exon 4 and the neo cassette. Western blot analysis confirmed the absence of protein expression in brain microsomes from homozygous mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

8 Publication categories

Trail: Allele