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Allele : Pate4<tm1.1(KOMP)Mbp> prostate and testis expressed 4; targeted mutation 1.1, Mouse Biology Program, UC Davis

Primary Identifier  MGI:5614597 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Pate4
Transmission  Germline Strain of Origin  C57BL/6N-A<tm1Brd>
Is Recombinase  false Is Wild Type  false
Project Collection  KOMP-CSD
molecularNote  The insertion of the L1L2_Bact_P cassette created a deletion of size 146 starting at position 35519501 and ending at position 35519647 of Chromosome 9 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site was followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site and subsequent Cre-mediated excision deleted the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

6 Publication categories